Initial regimens for the treatment-naive patient: current understanding and practice.

Since the introduction of highly active antiretroviral therapy in the mid-1990s, antiretroviral therapy (ART) options have expanded considerably to include simpler, safer, and more tolerable regimens. This has included new options for initial regimens for treatment-naive patients as well as regimens for treatment-experienced patients with extensive drug resistance. Current regimen options are easier, better tolerated, less toxic, more effective, and more durable than regimens used in the early years of the HAART era.